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4-IPP

Product Specifications

CAS Number

41270-96-6

Synonyms

4-Iodo-6-phenylpyrimidine

Target

MIF

Applications

Immunology & Inflammation

Smiles

C1=CC=C (C=C1) C2=CC (=NC=N2) I

Molecular Formula

C10H7IN2

Additionnal Information

4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) and a specific suicide substrate for MIF. 4-IPP can inhibit receptor activator of NF-κB ligand (RANKL) -induced osteoclastogenesis and potentiate osteoblast-mediated mineralization and bone nodule formation in vitro.

Storage Conditions

3 years -20°C powder

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