4-IPP
Product Specifications
CAS Number
41270-96-6
Synonyms
4-Iodo-6-phenylpyrimidine
Target
MIF
Applications
Immunology & Inflammation
Smiles
C1=CC=C (C=C1) C2=CC (=NC=N2) I
Molecular Formula
C10H7IN2
Additionnal Information
4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) and a specific suicide substrate for MIF. 4-IPP can inhibit receptor activator of NF-κB ligand (RANKL) -induced osteoclastogenesis and potentiate osteoblast-mediated mineralization and bone nodule formation in vitro.
Storage Conditions
3 years -20°C powder
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