CCT128930
Product Specifications
CAS Number
885499-61-6
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
C1CN (CCC1 (CC2=CC=C (C=C2) Cl) N) C3=NC=NC4=C3C=CN4
Molecular Formula
C18H20ClN5
Additionnal Information
CCT128930 is a potent, ATP-competitive and selective inhibitor of Akt2 with IC50 of 6 nM in a cell-free assay, 28-fold greater selectivity for Akt2 than the closely related PKA kinase. CCT128930 induces cell cycle arrest, DNA damage, and autophagy independent of Akt inhibition. High dose of CCT128930 triggers cell apoptosis in HepG2 cells.
Storage Conditions
2 years -80 in solvent
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