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Gedatolisib (PKI-587)

Product Specifications

CAS Number

1197160-78-3

Synonyms

PF-05212384

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CN (C) C1CCN (CC1) C (=O) C2=CC=C (C=C2) NC (=O) NC3=CC=C (C=C3) C4=NC (=NC (=N4) N5CCOCC5) N6CCOCC6

Molecular Formula

C32H41N9O4

Additionnal Information

Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.

Storage Conditions

2 years -80 in solvent

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