Mifepristone
Product Specifications
CAS Number
84371-65-3
Synonyms
C-1073, RU 38486
Target
Estrogen/progestogen Receptor
Applications
Endocrinology & Hormones
Smiles
CC#CC1 (CCC2C1 (CC (C3=C4CCC (=O) C=C4CCC23) C5=CC=C (C=C5) N (C) C) C) O
Molecular Formula
C29H35NO2
Additionnal Information
Mifepristone is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1.Mifepristone (RU486) can be used to induce animal models of Spontaneous Abortion.
Storage Conditions
2 years -80 in solvent
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