Rosiglitazone
Product Specifications
CAS Number
122320-73-4
Synonyms
BRL 49653
Target
PPAR
Applications
DNA Damage/DNA Repair
Smiles
CN (CCOC1=CC=C (C=C1) CC2C (=O) NC (=O) S2) C3=CC=CC=N3
Molecular Formula
C18H19N3O3S
Additionnal Information
Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.
Storage Conditions
2 years -80 in solvent
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