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Rosiglitazone

Product Specifications

CAS Number

122320-73-4

Synonyms

BRL 49653

Target

PPAR

Applications

DNA Damage/DNA Repair

Smiles

CN (CCOC1=CC=C (C=C1) CC2C (=O) NC (=O) S2) C3=CC=CC=N3

Molecular Formula

C18H19N3O3S

Additionnal Information

Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.

Storage Conditions

2 years -80 in solvent

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