Mitoxantrone 2HCl
Product Specifications
CAS Number
70476-82-3
Synonyms
NSC-301739 2HCl, Mitozantrone 2HCl
Target
Topoisomerase
Applications
DNA Damage/DNA Repair
Smiles
C1=CC (=C2C (=C1NCCNCCO) C (=O) C3=C (C=CC (=C3C2=O) O) O) NCCNCCO.Cl.Cl
Molecular Formula
C22H29ClN4O6.2HCl
Additionnal Information
Mitoxantrone 2HCl is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.
Storage Conditions
2 years -80 in solvent
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