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Mitoxantrone 2HCl

Product Specifications

CAS Number

70476-82-3

Synonyms

NSC-301739 2HCl, Mitozantrone 2HCl

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

C1=CC (=C2C (=C1NCCNCCO) C (=O) C3=C (C=CC (=C3C2=O) O) O) NCCNCCO.Cl.Cl

Molecular Formula

C22H29ClN4O6.2HCl

Additionnal Information

Mitoxantrone 2HCl is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis.

Storage Conditions

2 years -80 in solvent

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