Imatinib
Product Specifications
CAS Number
152459-95-5
Synonyms
STI571, CGP-57148B
Target
PDGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) NC (=O) C2=CC=C (C=C2) CN3CCN (CC3) C) NC4=NC=CC (=N4) C5=CN=CC=C5
Molecular Formula
C29H31N7O
Additionnal Information
Imatinib is a multi-target inhibitor of tyrosine kinase with inhibition for v-Abl, c-Kit and PDGFR, IC50 values are 0.6 μM, 0.1 μM and 0.1 μM in cell-free or cell-based assays, respectively. Imatinib (STI571) induces autophagy.
Storage Conditions
2 years -80 in solvent
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