Sodium stibogluconate
Product Specifications
CAS Number
16037-91-5
Synonyms
SSG, Stibogluconate sodium, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001
Target
Phosphatase
Applications
Metabolism
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O.O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+].OCC (O) C1O[Sb]2 (O) (OC1C (O2) C ([O-]) =O) O[Sb]34 ([O-]) OC (C (O) CO) C (O3) C (O4) C ([O-]) =O
Molecular Formula
C12H35Na3O26Sb2
Additionnal Information
Sodium stibogluconate (SSG, Stibogluconate trisodium nonahydrate, Lenocta, VQD-001), a pentavalent antimony derivative, is a potent and selective inhibitor of protein tyrosine phosphatase (PTPase) . Sodium stibogluconate inhibits 99% of Src homology 2 domain-containing phosphatase 1 (SHP-1) activity at 10 μg/ml and similar degrees of inhibition of SHP-2 and PTP1B requires 100 μg/ml. Sodium stibogluconate is a drug used in treatment of leishmaniasis.
Storage Conditions
3 years -20°C powder
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