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Cryptotanshinone (Tanshinone C)

Product Specifications

CAS Number

35825-57-1

Target

STAT

Applications

Apoptosis

Molecular Formula

C19H20O3

Additionnal Information

Cryptotanshinone (Tanshinone C) is a STAT3 inhibitor with IC50 of 4.6 μM in a cell-free assay, strongly inhibits phosphorylation of STAT3 Tyr705, with a small effect on STAT3 Ser727, but none against STAT1 nor STAT5. Cryptotanshinone induces ROS-dependent autophagy and mitochondria-mediated apoptosis.

Storage Conditions

2 years -80 in solvent

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