Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

HFSH-β- (33-53) (TFA)

HFSH-β- (33-53) TFA, a thiol-containing peptide which corresponds to a second FSH receptor-binding domain, is a FSHR (follicle-stimulating hormone receptor) antagonist. hFSH-β- (33-53) TFA inhibits binding of FSH to receptor and is a partial agonist of estradiol synthesis in Sertoli cells[1][2][3].

Product Specifications

UNSPSC

12352209

Target

Estrogen Receptor/ERR

Type

Peptides

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hfsh-β-33-53-tfa.html

Purity

99.16

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(CCC1)C([C@H](CC(O)=O)NC([C@H](CCCCN)NC([C@@H](NC([C@H](C(C)C)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H]([C@H](O)C)NC([C@@H](N)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](CCCCN)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CS)C(N[C@@H]([C@H](O)C)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C115H183N31O32S.xC2HF3O2

Molecular Weight

2543.94 (free acid)

References & Citations

[1]Grasso P, et al. A synthetic peptide corresponding to hFSH-beta- (81-95) has thioredoxin-like activity. Mol Cell Endocrinol. 1991;78 (3) :163-170. |[2]Xu Y, et al. Pilot study of a novel (18) F-labeled FSHR probe for tumor imaging. Mol Imaging Biol. 2014;16 (4) :578-585. |[3]Santa-Coloma TA, et al. Serine analogues of hFSH-beta- (33-53) and hFSH-beta- (81-95) inhibit hFSH binding to receptor. Biochem Biophys Res Commun. 1992;184 (3) :1273-1279.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD44 Human Gene Knockout Kit (CRISPR)
KN402455 1 Kit

CD44 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
4-Benzyl N-Carbobenzoxy-L-aspartate
TRC-B130523-500MG 500 mg

4-Benzyl N-Carbobenzoxy-L-aspartate

Sign In for Pricing
View Details
Elab Fluor® 647 Anti-Human CD305 Antibody[NKTA255]
AN00330M-01 20 Tests

Elab Fluor® 647 Anti-Human CD305 Antibody[NKTA255]

Sign In for Pricing
View Details
Elab Fluor® 647 Anti-Human CD305 Antibody[NKTA255]
AN00330M-02 100 Tests

Elab Fluor® 647 Anti-Human CD305 Antibody[NKTA255]

Sign In for Pricing
View Details
Elab Fluor® 647 Anti-Human CD305 Antibody[NKTA255]
AN00330M-03 2x 100 Tests

Elab Fluor® 647 Anti-Human CD305 Antibody[NKTA255]

Sign In for Pricing
View Details
Laboratory Water Purification System BLPS-504
BLPS-504 1 Unit

Laboratory Water Purification System BLPS-504

Sign In for Pricing
View Details