Silmitasertib (CX-4945)
Product Specifications
CAS Number
1009820-21-6
Target
Casein Kinase
Applications
Cell Cycle
Smiles
C1=CC (=CC (=C1) Cl) NC2=NC3=C (C=CC (=C3) C (=O) O) C4=C2C=CN=C4
Molecular Formula
C19H12ClN3O2
Additionnal Information
Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay) . Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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