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Degrasyn (WP1130)

Product Specifications

CAS Number

856243-80-6

Target

Bcr-Abl

Applications

Protein Tyrosine Kinase

Smiles

CCCC (C1=CC=CC=C1) NC (=O) C (=CC2=NC (=CC=C2) Br) C#N

Molecular Formula

C19H18BrN3O

Additionnal Information

Degrasyn (WP1130) is a selective deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor and also suppresses Bcr/Abl, also a JAK2 transducer (without affecting 20S proteasome) and activator of transcription (STAT) . Degrasyn (WP1130) induces apoptosis and blocks autophagy.

Storage Conditions

2 years -80 in solvent

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