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PF-3716556

Product Specifications

CAS Number

928774-43-0

Target

ATPase

Applications

Transmembrane Transporters

Smiles

CC1=C2C (CCOC2=CC=C1) NC3=CC (=CN4C3=NC (=C4) C) C (=O) N (C) CCO

Molecular Formula

C22H26N4O3

Additionnal Information

PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+, K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+, K+-ATPase, used for the treatment of gastroesophageal reflux disease.

Storage Conditions

2 years -80 in solvent

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