PF-3716556
Product Specifications
CAS Number
928774-43-0
Target
ATPase
Applications
Transmembrane Transporters
Smiles
CC1=C2C (CCOC2=CC=C1) NC3=CC (=CN4C3=NC (=C4) C) C (=O) N (C) CCO
Molecular Formula
C22H26N4O3
Additionnal Information
PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+, K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+, K+-ATPase, used for the treatment of gastroesophageal reflux disease.
Storage Conditions
2 years -80 in solvent
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