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Apatinib (YN968D1) mesylate

Product Specifications

CAS Number

1218779-75-9

Synonyms

YN968D1, Rivoceranib

Target

VEGFR

Applications

Protein Tyrosine Kinase

Smiles

C[S] (O) (=O) =O.O=C (NC1=CC=C (C=C1) C2 (CCCC2) C#N) C3=CC=CN=C3NCC4=CC=NC=C4

Molecular Formula

C25H27N5O4S

Additionnal Information

Apatinib mesylate (YN968D1, Rivoceranib) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib mesylate induces both autophagy and apoptosis.

Storage Conditions

2 years -80 in solvent

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