Mubritinib (TAK 165)
Product Specifications
CAS Number
366017-09-6
Target
HER2
Applications
Protein Tyrosine Kinase
Smiles
C1=CC (=CC=C1CCCCN2C=CN=N2) OCC3=COC (=N3) C=CC4=CC=C (C=C4) C (F) (F) F
Molecular Formula
C25H23F3N4O2
Additionnal Information
Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.
Storage Conditions
2 years -80 in solvent
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