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Mubritinib (TAK 165)

Product Specifications

CAS Number

366017-09-6

Target

HER2

Applications

Protein Tyrosine Kinase

Smiles

C1=CC (=CC=C1CCCCN2C=CN=N2) OCC3=COC (=N3) C=CC4=CC=C (C=C4) C (F) (F) F

Molecular Formula

C25H23F3N4O2

Additionnal Information

Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell; no activity to EGFR, FGFR, PDGFR, JAK1, Src and Blk in BT-474 cell line.

Storage Conditions

2 years -80 in solvent

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