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AZ 960

Product Specifications

CAS Number

905586-69-8

Target

JAK

Applications

Angiogenesis

Smiles

CC1=CC (=NN1) NC2=C (C=C (C (=N2) NC (C) C3=CC=C (C=C3) F) C#N) F

Molecular Formula

C18H16F2N6

Additionnal Information

AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3. AZ 960 induces apoptosis and growth arrest.

Storage Conditions

2 years -80 in solvent

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