AZ 960
Product Specifications
CAS Number
905586-69-8
Target
JAK
Applications
Angiogenesis
Smiles
CC1=CC (=NN1) NC2=C (C=C (C (=N2) NC (C) C3=CC=C (C=C3) F) C#N) F
Molecular Formula
C18H16F2N6
Additionnal Information
AZ 960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki of <3 nM and 0.45 nM, 3-fold selectivity of AZ960 for JAK2 over JAK3. AZ 960 induces apoptosis and growth arrest.
Storage Conditions
2 years -80 in solvent
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