NVP-BHG712
Product Specifications
CAS Number
940310-85-0
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C=C (C=C1) C (=O) NC2=CC=CC (=C2) C (F) (F) F) NC3=C4C=NN (C4=NC (=N3) C5=CN=CC=C5) C
Molecular Formula
C26H20F3N7O
Additionnal Information
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src and c-Abl with IC50 of 0.395 μM, 1.266 μM and 1.667 μM, respectively.
Storage Conditions
2 years -80 in solvent
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