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BMS-794833

Product Specifications

CAS Number

1174046-72-0

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

C1=CC (=CC=C1C2=CNC=C (C2=O) C (=O) NC3=CC (=C (C=C3) OC4=C (C (=NC=C4) N) Cl) F) F

Molecular Formula

C23H15ClF2N4O3

Additionnal Information

BMS-794833 is a potent ATP competitive inhibitor of Met (c-Met) /VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.

Storage Conditions

2 years -80 in solvent

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