R406
Product Specifications
CAS Number
841290-81-1
Synonyms
R406 besylate
Target
FLT3
Applications
Protein Tyrosine Kinase
Smiles
CC1 (C (=O) NC2=C (O1) C=CC (=N2) NC3=NC (=NC=C3F) NC4=CC (=C (C (=C4) OC) OC) OC) C.C1=CC=C (C=C1) S (=O) (=O) O
Molecular Formula
C22H23FN6O5.C6H6O3S
Additionnal Information
R406 (R406 besylate) is a potent Syk inhibitor with IC50 of 41 nM in cell-free assays, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 induces apoptosis. Phase 1.
Storage Conditions
2 years -80 in solvent
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