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SB505124

Product Specifications

CAS Number

694433-59-5

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CC1=NC (=CC=C1) C2=C (N=C (N2) C (C) (C) C) C3=CC4=C (C=C3) OCO4

Molecular Formula

C20H21N3O2

Additionnal Information

SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM in cell-free assays, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.

Storage Conditions

2 years -80 in solvent

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