What is the catalog number for Ixazomib (MLN2238)?

The catalog number for Ixazomib (MLN2238) is C08336-5mg.

What sizes are available for Ixazomib (MLN2238)?

Ixazomib (MLN2238) is available in the following size(s): 5 mg.

Is Ixazomib (MLN2238) in stock?

Ixazomib (MLN2238) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Ixazomib (MLN2238)?

Ixazomib (MLN2238) is requires dry ice shipping.

Ixazomib (MLN2238)

Product Specifications

CAS Number

1072833-77-2

Target

Proteasome

Applications

Proteases

Smiles

B (C (CC (C) C) NC (=O) CNC (=O) C1=C (C=CC (=C1) Cl) Cl) (O) O

Molecular Formula

C14H19BCl2N2O4

Additionnal Information

Ixazomib (MLN2238) inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM in cell-free assays, respectively, also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites, with IC50 of 31 and 3500 nM. Ixazomib (MLN2238) induces autophagy. Phase 3.