Gandotinib (LY2784544)
Product Specifications
CAS Number
1229236-86-5
Target
JAK
Applications
Angiogenesis
Smiles
CC1=CC (=NN1) NC2=NN3C (=C (N=C3C (=C2) CN4CCOCC4) C) CC5=C (C=C (C=C5) Cl) F
Molecular Formula
C23H25ClFN7O
Additionnal Information
Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.
Storage Conditions
2 years -80 in solvent
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