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Gandotinib (LY2784544)

Product Specifications

CAS Number

1229236-86-5

Target

JAK

Applications

Angiogenesis

Smiles

CC1=CC (=NN1) NC2=NN3C (=C (N=C3C (=C2) CN4CCOCC4) C) CC5=C (C=C (C=C5) Cl) F

Molecular Formula

C23H25ClFN7O

Additionnal Information

Gandotinib (LY2784544) is a potent JAK2 inhibitor with IC50 of 3 nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.

Storage Conditions

2 years -80 in solvent

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