What is the catalog number for RAF265 (CHIR-265)?

The catalog number for RAF265 (CHIR-265) is C16674-100mg.

What sizes are available for RAF265 (CHIR-265)?

RAF265 (CHIR-265) is available in the following size(s): 100 mg.

Is RAF265 (CHIR-265) in stock?

RAF265 (CHIR-265) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for RAF265 (CHIR-265)?

RAF265 (CHIR-265) is requires dry ice shipping.

RAF265 (CHIR-265)

Product Specifications

CAS Number

927880-90-8

Target

Raf

Applications

MAPK

Smiles

CN1C2=C (C=C (C=C2) OC3=CC (=NC=C3) C4=NC=C (N4) C (F) (F) F) N=C1NC5=CC=C (C=C5) C (F) (F) F

Molecular Formula

C24H16F6N6O

Additionnal Information

RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM in cell-free assays. RAF265 (CHIR-265) induces cell cycle arrest and apoptosis. Phase 2.