What is the catalog number for Pioglitazone HCl?

The catalog number for Pioglitazone HCl is C08234-200mg.

What sizes are available for Pioglitazone HCl?

Pioglitazone HCl is available in the following size(s): 200 mg.

Is Pioglitazone HCl in stock?

Pioglitazone HCl is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Pioglitazone HCl?

Pioglitazone HCl is requires dry ice shipping.

Pioglitazone HCl

Product Specifications

CAS Number

112529-15-4

Synonyms

AD-4833, U-72107E

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

CCC1=CN=C (C=C1) CCOC2=CC=C (C=C2) CC3C (=O) NC (=O) S3.Cl

Molecular Formula

C19H20N2O3S.HCl

Additionnal Information

Pioglitazone HCl (AD-4833, U-72107E) is an inhibitor of cytochrome P450 (CYP) 2C8 and CYP3A4 enzymes. Pioglitazone HCl inhibits CYP2C8, CYP3A4 and CYP2C9 with Ki of 1.7 μM, 11.8 μM and 32.1 μM, respectively. Pioglitazone HCl is also a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist with EC50 of 0.93 μM and 0.99 μM for human PPARγ and mouse PPARγ, respectively. Pioglitazone HCl inhibits mitochondrial iron uptake, lipid peroxidation, and subsequent ferroptosis.