PF-573228
Product Specifications
CAS Number
869288-64-2
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CS (=O) (=O) C1=CC=CC (=C1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) CC4
Molecular Formula
C22H20F3N5O3S
Additionnal Information
PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1254240-01 0.02 mg (E-Coli)
Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
Sign In for Pricing
View Details MBS1254240-02 0.02 mg (Yeast)
Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
Sign In for Pricing
View Details MBS1254240-03 0.1 mg (E-Coli)
Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
Sign In for Pricing
View Details MBS1254240-04 0.1 mg (Yeast)
Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
Sign In for Pricing
View Details MBS1254240-05 0.02 mg (Baculovirus)
Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2)
Sign In for Pricing
View Details