PF-573228
Product Specifications
CAS Number
869288-64-2
Target
FAK
Applications
Protein Tyrosine Kinase
Smiles
CS (=O) (=O) C1=CC=CC (=C1) CNC2=NC (=NC=C2C (F) (F) F) NC3=CC4=C (C=C3) NC (=O) CC4
Molecular Formula
C22H20F3N5O3S
Additionnal Information
PF-573228 is an ATP-competitive inhibitor of FAK with IC50 of 4 nM in a cell-free assay, ~50- to 250-fold selective for FAK than Pyk2, CDK1/7 and GSK-3β. PF-573228 induces apoptosis.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
bs-14181R-BF555 100 µL
Cytochrome p450 2J2 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Sign In for Pricing
View Details NBP2-99388MFV450 0.1 mL
Rabbit Polyclonal alpha Adducin Antibody [mFluor Violet 450 SE]
Sign In for Pricing
View Details 
GTR15159188 1 Vial
Lentiviral mouse Haus2 shRNA (UAS) - Lentiviral mouseHaus2 shRNA (UAS, GFP) (25)
Sign In for Pricing
View Details 
MBS1283740 Inquire
Recombinant Pseudomonas fluorescens Valine--tRNA ligase (valS), partial
Sign In for Pricing
View Details