Indirubin-3'-monoxime
Product Specifications
CAS Number
160807-49-8
Synonyms
Indirubin-3'-oxime
Target
CDK
Applications
Cell Cycle
Smiles
C1=CC=C2C (=C1) C (=C (N2) O) C3=C (C4=CC=CC=C4N3) N=O
Molecular Formula
C16H11N3O2
Additionnal Information
Indirubin-3'-monoxime (Indirubin-3'-oxime) is a selective CDK inhibitor with IC50 of 0.18 μM, 0.44 μM, 0.25 μM, 3.33 μM, 0.065 μM for CDK1-cyclinB, CDK2-cyclinA, CDK2-cyclinE, CDK4-cyclinD1, CDK5-p35, respectively. Indirubin-3'-monoxime is a direct and selective 5-lipoxygenase inhibitor with IC50 of 7.8-10 μM.
Storage Conditions
3 years -20°C powder
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