Thioguanine
Product Specifications
CAS Number
154-42-7
Synonyms
NSC 752, 6-Thioguanine, 2-Amino-6-purinethiol
Target
DNA Methyltransferase
Applications
Epigenetics
Smiles
C1=NC2=C (N1) C (=S) N=C (N2) N
Molecular Formula
C5H5N5S
Additionnal Information
Thioguanine, a purine antimetabolite, inhibits DNMT1 activity through ubiquitin-targeted degradation, used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients.
Storage Conditions
2 years -80 in solvent
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