Deferasirox

Product Specifications

CAS Number

201530-41-8

Synonyms

CGP-72670, ICL-670

Target

P450 (e.g. CYP17)

Applications

Metabolism

Smiles

C1=CC=C (C (=C1) C2=NN (C (=N2) C3=CC=CC=C3O) C4=CC=C (C=C4) C (=O) O) O

Molecular Formula

C21H15N3O4

Additionnal Information

Deferasirox is an iron chelator, also a cytochrome P450 3A4 inducer, Cytochrome P450 2C8 inhibitor, and Cytochrome P450 1A2 inhibitor. Deferasirox-induced iron depletion promotes BclxL downregulation and cell death.

Storage Conditions

2 years -80 in solvent

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