Disulfiram
Product Specifications
CAS Number
97-77-8
Synonyms
NSC 190940, Tetraethylthiuram disulfide, TETD
Target
Dehydrogenase
Applications
Metabolism
Smiles
CCN (CC) C (=S) SSC (=S) N (CC) CC
Molecular Formula
C10H20N2S4
Additionnal Information
Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH) with IC50 of 0.15 μM and 1.45 μM for hALDH1 and hALDH2, respectively. Disulfiram is used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram induces apoptosis. Disulfiram is also an inhibitor of pore formation by gasdermin D (GSDMD) .
Storage Conditions
2 years -80 in solvent
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