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H 89 2HCl

Product Specifications

CAS Number

130964-39-5

Target

PKA

Applications

Stem Cells & Wnt

Smiles

C1=CC2=C (C=CN=C2) C (=C1) S (=O) (=O) NCCNCC=CC3=CC=C (C=C3) Br.Cl.Cl

Molecular Formula

C20H20BrN3O2S.2HCl

Additionnal Information

H 89 2HCl is a potent PKA inhibitor with Ki of 48 nM in a cell-free assay, 10-fold selective for PKA than PKG,500-fold greater selectivity than PKC, MLCK, calmodulin kinase II and casein kinase I/II. H 89 2HCl induces autophagy.

Storage Conditions

2 years -80 in solvent

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