Palbociclib (PD-0332991) Isethionate
Product Specifications
CAS Number
827022-33-3
Synonyms
PD0332991 Isethionate
Target
CDK
Applications
Cell Cycle
Smiles
CC1=C (C (=O) N (C2=NC (=NC=C12) NC3=NC=C (C=C3) N4CCNCC4) C5CCCC5) C (=O) C.C (CS (=O) (=O) O) O
Molecular Formula
C24H29N7O2.C2H6O4S
Additionnal Information
Palbociclib Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM in cell-free assays. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 3.
Storage Conditions
2 years -80 in solvent
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