Lumacaftor (VX-809)
Product Specifications
CAS Number
936727-05-8
Synonyms
VRT 826809
Target
CFTR
Applications
Transmembrane Transporters
Smiles
CC1=C (N=C (C=C1) NC (=O) C2 (CC2) C3=CC4=C (C=C3) OC (O4) (F) F) C5=CC (=CC=C5) C (=O) O
Molecular Formula
C24H18F2N2O5
Additionnal Information
Lumacaftor (VX-809, VRT 826809) acts to correct CFTR mutations common in cystic fibrosis by increasing mutant CFTR (F508del-CFTR) maturation, EC50 of 0.1 μM in fisher rat thyroid cells. Phase 3.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS642042-01 0.05 mg
Aminoadipate Aminotransferase (AADAT, AadAT, KAT2, KATII, kynurenine aminotransferase II)
Sign In for Pricing
View Details MBS642042-02 5x 0.05 mg
Aminoadipate Aminotransferase (AADAT, AadAT, KAT2, KATII, kynurenine aminotransferase II)
Sign In for Pricing
View Details RC227720L2V 200 µL
SIRT1 (NM_001142498) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details 
MBS6182129-01 0.1 mL
SOLH (Small Pptic lobes Homolog (Drosophila), CAPN15, MGC131491) (HRP)
Sign In for Pricing
View Details MBS6182129-02 5x 0.1 mL
SOLH (Small Pptic lobes Homolog (Drosophila), CAPN15, MGC131491) (HRP)
Sign In for Pricing
View Details 