BMS-777607
Product Specifications
CAS Number
1025720-94-8
Synonyms
BMS 817378
Target
Axl
Applications
Protein Tyrosine Kinase
Smiles
CCOC1=C (C (=O) N (C=C1) C2=CC=C (C=C2) F) C (=O) NC3=CC (=C (C=C3) OC4=C (C (=NC=C4) N) Cl) F
Molecular Formula
C25H19ClF2N4O4
Additionnal Information
BMS-777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM in cell-free assays, 40-fold more selective for Met-related targets versus Lck, VEGFR-2, and TrkA/B, and more than 500-fold greater selectivity versus all other receptor and non receptor kinases.
Storage Conditions
2 years -80 in solvent
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