KRN 633
Product Specifications
CAS Number
286370-15-8
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CCCNC (=O) NC1=C (C=C (C=C1) OC2=NC=NC3=CC (=C (C=C32) OC) OC) Cl
Molecular Formula
C20H21ClN4O4
Additionnal Information
KRN 633 is an ATP-competitive inhibitor of VEGFR1/2/3 with IC50 of 170 nM/160 nM/125 nM, weakly inhibits PDGFR-α/β and c-Kit, does not block the phosphorylation of FGFR-1, EGFR or c-Met in cell.
Storage Conditions
2 years -80 in solvent
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