R406 (free base)
Product Specifications
CAS Number
841290-80-0
Target
Syk
Applications
Protein Tyrosine Kinase
Smiles
CC1 (C (=O) NC2=C (O1) C=CC (=N2) NC3=NC (=NC=C3F) NC4=CC (=C (C (=C4) OC) OC) OC) C
Molecular Formula
C22H23FN6O5
Additionnal Information
R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. R406 (free base) triggers apoptosis. Phase 1.
Storage Conditions
2 years -80 in solvent
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