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BIX 02188

Product Specifications

CAS Number

1094614-84-2

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

CN (C) CC1=CC (=CC=C1) N=C (C2=CC=CC=C2) C3=C (NC4=C3C=CC (=C4) C (=O) N) O

Molecular Formula

C25H24N4O2

Additionnal Information

BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.

Storage Conditions

2 years -80 in solvent

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