BIX 02188
Product Specifications
CAS Number
1094614-84-2
Target
MEK
Applications
Protein Tyrosine Kinase
Smiles
CN (C) CC1=CC (=CC=C1) N=C (C2=CC=CC=C2) C3=C (NC4=C3C=CC (=C4) C (=O) N) O
Molecular Formula
C25H24N4O2
Additionnal Information
BIX02188 is a selective inhibitor of MEK5 with IC50 of 4.3 nM, also inhibits ERK5 catalytic activity with IC50 of 810 nM, and does not inhibit closely related kinases MEK1, MEK2, ERK2, and JNK2.
Storage Conditions
2 years -80 in solvent
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