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Adavosertib (MK-1775)

Product Specifications

CAS Number

955365-80-7

Synonyms

AZD1775

Target

Wee1

Applications

Cell Cycle

Smiles

CC (C) (C1=NC (=CC=C1) N2C3=NC (=NC=C3C (=O) N2CC=C) NC4=CC=C (C=C4) N5CCN (CC5) C) O

Molecular Formula

C27H32N8O2

Additionnal Information

Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. Phase 2.

Storage Conditions

2 years -80 in solvent

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