AT7519
Product Specifications
CAS Number
844442-38-2
Synonyms
AT7519M
Target
CDK
Applications
Cell Cycle
Smiles
C1CNCCC1NC (=O) C2=C (C=NN2) NC (=O) C3=C (C=CC=C3Cl) Cl
Molecular Formula
C16H17Cl2N5O2
Additionnal Information
AT7519 is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM. It is less potent to CDK3 and little active to CDK7. AT7519 also decrease GSK3β phosphorylation. AT7519 induces apoptosis. Phase 2.
Storage Conditions
2 years -80 in solvent
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