Pralatrexate
Product Specifications
CAS Number
146464-95-1
Synonyms
NSC 754230
Target
DHFR
Applications
Cell Cycle
Smiles
C#CCC (CC1=CN=C2C (=N1) C (=NC (=N2) N) N) C3=CC=C (C=C3) C (=O) NC (CCC (=O) O) C (=O) O
Molecular Formula
C23H23N7O5
Additionnal Information
Pralatrexate is an antifolate, and structurally a folate analog. Its IC50 is < 300 nM in some cell lines. Pralatrexate induces tumor cell apoptosis.
Storage Conditions
2 years -80 in solvent
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