PHA-793887
Product Specifications
CAS Number
718630-59-2
Target
CDK
Applications
Cell Cycle
Smiles
CC (C) CC (=O) NC1=NNC2=C1CN (C2 (C) C) C (=O) C3CCN (CC3) C
Molecular Formula
C19H31N5O2
Additionnal Information
PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. PHA-793887 induces cell-cycle arrest and apoptosis. Phase 1.
Storage Conditions
2 years -80 in solvent
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