AEE788 (NVP-AEE788)
Product Specifications
CAS Number
497839-62-0
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CCN1CCN (CC1) CC2=CC=C (C=C2) C3=CC4=C (N3) N=CN=C4NC (C) C5=CC=CC=C5
Molecular Formula
C27H32N6
Additionnal Information
AEE788 (NVP-AEE788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKCα and CDK1. Phase 1/2.
Storage Conditions
2 years -80 in solvent
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